Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 5
Ligand
BDBM50351150
Substrate
n/a
Meas. Tech.
ChEMBL_829140 (CHEMBL2059962)
IC50
48100±n/a nM
Citation
 Zhang, Y; Arnatt, CK; Zhang, F; Wang, J; Haney, KM; Fang, X The potential role of anibamine, a natural product CCR5 antagonist, and its analogues as leads toward development of anti-ovarian cancer agents. Bioorg Med Chem Lett 22:5093-7 (2012) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 5
Synonyms:
C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor
Type:
Enzyme
Mol. Mass.:
40540.21
Organism:
Homo sapiens (Human)
Description:
P51681
Residue:
352
Sequence:
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
  
Inhibitor
Name:
BDBM50351150
Synonyms:
CHEMBL1817915 | CHEMBL2057817
Type:
Small organic molecule
Emp. Form.:
C32H54N
Mol. Mass.:
452.7773
SMILES:
CCCCCCCC\C=C\c1c(C)c(\C=C\CCCCCCCC)c2CCCCC[n+]2c1C
Structure:
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