Reaction Details Report a problem with these data
Target
N-acetyllactosaminide alpha-1,3-galactosyltransferase
Ligand
BDBM50389789
Substrate
n/a
Meas. Tech.
ChEMBL_834314 (CHEMBL2073134)
Ki
9800±n/a nM
Citation
 Descroix, K; Pesnot, T; Yoshimura, Y; Gehrke, SS; Wakarchuk, W; Palcic, MM; Wagner, GK Inhibition of galactosyltransferases by a novel class of donor analogues. J Med Chem 55:2015-24 (2012) [PubMed]  Article 
Target
Name:
N-acetyllactosaminide alpha-1,3-galactosyltransferase
Synonyms:
GGTA1 | GGTA1_BOVIN | Galactosyltransferase | UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase
Type:
PROTEIN
Mol. Mass.:
43245.99
Organism:
Bos taurus
Description:
ChEMBL_834314
Residue:
368
Sequence:
MNVKGKVILSMLVVSTVIVVFWEYIHSPEGSLFWINPSRNPEVGGSSIQKGWWLPRWFNNGYHEEDGDINEEKEQRNEDESKLKLSDWFNPFKRPEVVTMTKWKAPVVWEGTYNRAVLDNYYAKQKITVGLTVFAVGRYIEHYLEEFLTSANKHFMVGHPVIFYIMVDDVSRMPLIELGPLRSFKVFKIKPEKRWQDISMMRMKTIGEHIVAHIQHEVDFLFCMDVDQVFQDKFGVETLGESVAQLQAWWYKADPNDFTYERRKESAAYIPFGEGDFYYHAAIFGGTPTQVLNITQECFKGILKDKKNDIEAQWHDESHLNKYFLLNKPTKILSPEYCWDYHIGLPADIKLVKMSWQTKEYNVVRNNV
  
Inhibitor
Name:
BDBM50389789
Synonyms:
CHEMBL1229737
Type:
Small organic molecule
Emp. Form.:
C20H26N2O18P2S
Mol. Mass.:
676.436
SMILES:
OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cc(-c3ccc(C=O)s3)c(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@H]1O |r|
Structure:
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