Reaction Details Report a problem with these data
Target
Hydroxycarboxylic acid receptor 1
Ligand
BDBM50336490
Substrate
n/a
Meas. Tech.
ChEMBL_850283 (CHEMBL2150703)
EC50
377000±n/a nM
Citation
 Dvorak, CA; Liu, C; Shelton, J; Kuei, C; Sutton, SW; Lovenberg, TW; Carruthers, NI Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects. ACS Med Chem Lett 3:637-639 (2012) [PubMed]  Article 
Target
Name:
Hydroxycarboxylic acid receptor 1
Synonyms:
G-protein coupled receptor 104 | GPR104 | GPR81 | HCA1 | HCAR1 | HCAR1_HUMAN
Type:
PROTEIN
Mol. Mass.:
39313.04
Organism:
Homo sapiens (Human)
Description:
ChEMBL_850283
Residue:
346
Sequence:
MYNGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSARLYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPKQPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDPHIVEWH
  
Inhibitor
Name:
BDBM50336490
Synonyms:
3,5-DIHYDROXYBENZOATE | 3,5-Dihydroxy-benzoic acid | 3,5-Dihydroxybenzoate, IX | 3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicacid | CHEMBL95308
Type:
Small organic molecule
Emp. Form.:
C7H6O4
Mol. Mass.:
154.1201
SMILES:
OC(=O)c1cc(O)cc(O)c1
Structure:
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