Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50392806
Substrate
n/a
Meas. Tech.
ChEMBL_853298 (CHEMBL2155058)
Ki
2500±n/a nM
Citation
 Carlsson, J; Tosh, DK; Phan, K; Gao, ZG; Jacobson, KA Structure-activity relationships and molecular modeling of 1,2,4-triazoles as adenosine receptor antagonists. ACS Med Chem Lett 3:715-720 (2012) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50392806
Synonyms:
CHEMBL2151252
Type:
Small organic molecule
Emp. Form.:
C17H15ClN4O2
Mol. Mass.:
342.78
SMILES:
C[C@@H](Oc1ccc(Cl)cc1)C(=O)Nc1nnc([nH]1)-c1ccccc1 |r|
Structure:
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