Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50392826
Substrate
n/a
Meas. Tech.
ChEMBL_853298 (CHEMBL2155058)
Ki
1500±n/a nM
Citation
 Carlsson, J; Tosh, DK; Phan, K; Gao, ZG; Jacobson, KA Structure-activity relationships and molecular modeling of 1,2,4-triazoles as adenosine receptor antagonists. ACS Med Chem Lett 3:715-720 (2012) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50392826
Synonyms:
CHEMBL2151265
Type:
Small organic molecule
Emp. Form.:
C16H13FN4O2
Mol. Mass.:
312.2984
SMILES:
Fc1ccc(cc1)-c1nnc(NC(=O)COc2ccccc2)[nH]1
Structure:
Search PDB for entries with ligand similarity: