Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50394569
Substrate
n/a
Meas. Tech.
ChEMBL_856764 (CHEMBL2162732)
Ki
1120±n/a nM
Citation
 Rizzo, S; Tarozzi, A; Bartolini, M; Da Costa, G; Bisi, A; Gobbi, S; Belluti, F; Ligresti, A; Allarà, M; Monti, JP; Andrisano, V; Di Marzo, V; Hrelia, P; Rampa, A 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents. Eur J Med Chem 58:519-32 (2012) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50394569
Synonyms:
CHEMBL2160222
Type:
Small organic molecule
Emp. Form.:
C41H48N2O3
Mol. Mass.:
616.8314
SMILES:
CCN(CC)Cc1ccc(cc1)C(=O)c1c(oc2ccccc12)-c1ccc(OCCCCCCCN(C)Cc2ccccc2)cc1
Structure:
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