Reaction Details Report a problem with these data
Target
Carboxypeptidase B
Ligand
BDBM50395737
Substrate
n/a
Meas. Tech.
ChEMBL_860203 (CHEMBL2168943)
IC50
1.1±n/a nM
Citation
 Yoshimoto, N; Sasaki, T; Sugimoto, K; Ishii, H; Yamamoto, K Design and characterization of a selenium-containing inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa), a zinc-containing metalloprotease. J Med Chem 55:7696-705 (2012) [PubMed]  Article 
Target
Name:
Carboxypeptidase B
Synonyms:
CBPB1_PIG | CPB | CPB1
Type:
PROTEIN
Mol. Mass.:
47371.10
Organism:
Sus scrofa
Description:
ChEMBL_453905
Residue:
416
Sequence:
MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL
  
Inhibitor
Name:
BDBM50395737
Synonyms:
CHEMBL2164457
Type:
Small organic molecule
Emp. Form.:
C16H32N2O4Se2
Mol. Mass.:
474.36
SMILES:
NCCCCCC(C[Se][Se]CC(CCCCCN)C(O)=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: