Reaction Details Report a problem with these data
Target
Carboxypeptidase B
Ligand
BDBM50395728
Substrate
n/a
Meas. Tech.
ChEMBL_860206 (CHEMBL2168946)
IC50
4.9±n/a nM
Citation
 Yoshimoto, N; Sasaki, T; Sugimoto, K; Ishii, H; Yamamoto, K Design and characterization of a selenium-containing inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa), a zinc-containing metalloprotease. J Med Chem 55:7696-705 (2012) [PubMed]  Article 
Target
Name:
Carboxypeptidase B
Synonyms:
CBPB1_PIG | CPB | CPB1
Type:
PROTEIN
Mol. Mass.:
47371.10
Organism:
Sus scrofa
Description:
ChEMBL_453905
Residue:
416
Sequence:
MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL
  
Inhibitor
Name:
BDBM50395728
Synonyms:
CHEMBL2164463
Type:
Small organic molecule
Emp. Form.:
C21H35N2O5P
Mol. Mass.:
426.4868
SMILES:
CC(C)[C@H](NC(=O)CCc1ccccc1)P(O)(=O)C[C@@H](CCCCCN)C(O)=O |r|
Structure:
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