Reaction Details Report a problem with these data
Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50396141
Substrate
n/a
Meas. Tech.
ChEMBL_862589 (CHEMBL2173985)
Ki
20±n/a nM
Citation
 St Jean, DJ; Fotsch, C Mitigating heterocycle metabolism in drug discovery. J Med Chem 55:6002-20 (2012) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50396141
Synonyms:
CHEMBL2171708
Type:
Small organic molecule
Emp. Form.:
C22H28N4O5
Mol. Mass.:
428.4815
SMILES:
CC(C)OC(=O)N1C[C@@H]2COC[C@H](C1)[C@@H]2Oc1ncnc(Oc2cccnc2C)c1C |r|
Structure:
Search PDB for entries with ligand similarity: