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Target
Trace amine-associated receptor 1
Ligand
BDBM106574
Substrate
n/a
Meas. Tech.
ChEMBL_882011 (CHEMBL2213506)
EC50
28±n/a nM
Citation
 Galley, G; Stalder, H; Goergler, A; Hoener, MC; Norcross, RD Optimisation of imidazole compounds as selective TAAR1 agonists: discovery of RO5073012. Bioorg Med Chem Lett 22:5244-8 (2012) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM106574
Synonyms:
CHEMBL2206404 | US8586617, 7
Type:
Small organic molecule
Emp. Form.:
C13H17N3
Mol. Mass.:
215.2942
SMILES:
CC(C)N(Cc1cnc[nH]1)c1ccccc1
Structure:
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