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Target
Type-1 angiotensin II receptor
Ligand
BDBM50403238
Substrate
n/a
Meas. Tech.
ChEMBL_36318 (CHEMBL652267)
Kd
3.16±n/a nM
Citation
 Murray, W; Lalan, P; Gill, A; Lee, D; Falotico, R; Lewis, J; Addo, M; Wachter, M Substituted lactam biphenyltetrazoles as angiotensin II mediated antihypertensives Bioorg Med Chem Lett 4:87-92 (1994)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41009.15
Organism:
RABBIT
Description:
ANGIOTENSIN AT1 AGTR1 RABBIT::P34976
Residue:
359
Sequence:
MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
  
Inhibitor
Name:
BDBM50403238
Synonyms:
CHEMBL170196
Type:
Small organic molecule
Emp. Form.:
C26H27N5O3
Mol. Mass.:
457.5243
SMILES:
CCOC(=O)\C=C1/CC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Structure:
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