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Target
Thromboxane A2 receptor
Ligand
BDBM50403436
Substrate
n/a
Meas. Tech.
ChEMBL_90007 (CHEMBL701680)
IC50
2000±n/a nM
Citation
 Klar, U; Kuhnke, J; Pletsch, A; Rehwinkel, H; Schreyer, R Novel prostanoid thromboxane A2 antagonists Bioorg Med Chem Lett 5:1219-1224 (1995)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50403436
Synonyms:
CHEMBL21111
Type:
Small organic molecule
Emp. Form.:
C21H27FN2O4S
Mol. Mass.:
422.513
SMILES:
OC(=O)CCC\C=C/C[C@H]1[C@H](F)CC[C@@H]1NS(=O)(=O)C1=C2N=CC=CC2CC=C1 |c:20,22,24,29|
Structure:
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