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Target
Thromboxane A2 receptor
Ligand
BDBM50403453
Substrate
n/a
Meas. Tech.
ChEMBL_90007 (CHEMBL701680)
IC50
600±n/a nM
Citation
 Klar, U; Kuhnke, J; Pletsch, A; Rehwinkel, H; Schreyer, R Novel prostanoid thromboxane A2 antagonists Bioorg Med Chem Lett 5:1219-1224 (1995)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50403453
Synonyms:
CHEMBL282225
Type:
Small organic molecule
Emp. Form.:
C17H20N2O6S
Mol. Mass.:
380.415
SMILES:
OC(=O)CC\C=C/CC1=CCC[C@@H]1NS(=O)(=O)c1ccccc1[N+]([O-])=O |t:8|
Structure:
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