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Target
D(2) dopamine receptor
Ligand
BDBM50421506
Substrate
n/a
Meas. Tech.
ChEMBL_61942 (CHEMBL858397)
Ki
<10000±n/a nM
Citation
 Brown, A; Carlyle, I; Clark, J; Hamilton, W; Gibson, S; McGarry, G; McEachen, S; Rae, D; Thorn, S; Walker, G Discovery and SAR of org 24598-a selective glycine uptake inhibitor. Bioorg Med Chem Lett 11:2007-9 (2001) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50421506
Synonyms:
CHEMBL61861 | ORG-24598
Type:
Small organic molecule
Emp. Form.:
C19H19F3NO3
Mol. Mass.:
366.3548
SMILES:
CN(CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1)CC([O-])=O
Structure:
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