Reaction Details Report a problem with these data
Target
Beta-1 adrenergic receptor
Ligand
BDBM50405013
Substrate
n/a
Meas. Tech.
ChEMBL_39341 (CHEMBL653378)
Kd
5±n/a nM
Citation
 Bouzoubaa, M; Leclerc, G; Decker, N; Schwartz, J; Andermann, G Synthesis and beta-adrenergic blocking activity of new aliphatic and alicyclic oxime ethers. J Med Chem 27:1291-4 (1984) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50405013
Synonyms:
CHEMBL285972
Type:
Small organic molecule
Emp. Form.:
C14H26N2O2
Mol. Mass.:
254.3684
SMILES:
[#6]C([#6])([#6])[#7]-[#6]-[#6](-[#8])-[#6]-[#8]\[#7]=[#6](/[#6]-1-[#6]-[#6]1)-[#6]-1-[#6]-[#6]-1
Structure:
Search PDB for entries with ligand similarity: