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Target
Beta-1 adrenergic receptor
Ligand
BDBM50405147
Substrate
n/a
Meas. Tech.
ChEMBL_39343 (CHEMBL655647)
Kd
5.8±n/a nM
Citation
 Nelson, WL; Bartels, MJ; Bednarski, PJ; Zhang, S; Messick, K; Horng, JS; Ruffolo, RR The 3,4-catechol derivative of propranolol, a minor dihydroxylated metabolite. J Med Chem 27:857-61 (1984) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50405147
Synonyms:
4-HYDROXYPROPRANOLOL SULFATE | 4-Hydroxy Propranolol
Type:
Small organic molecule
Emp. Form.:
C16H21NO3
Mol. Mass.:
275.3428
SMILES:
CC(C)NCC(O)COc1ccc(O)c2ccccc12
Structure:
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