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Target
7-dehydrocholesterol reductase
Ligand
BDBM50406616
Substrate
n/a
Meas. Tech.
ChEMBL_53601 (CHEMBL665488)
Ki
48±n/a nM
Citation
 Ator, MA; Schmidt, SJ; Adams, JL; Dolle, RE; Kruse, LI; Frey, CL; Barone, JM Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase. J Med Chem 35:100-6 (1992) [PubMed]  Article 
Target
Name:
7-dehydrocholesterol reductase
Synonyms:
DHCR7_RAT | Dhcr7
Type:
PROTEIN
Mol. Mass.:
54168.97
Organism:
Rattus norvegicus
Description:
ChEMBL_53595
Residue:
471
Sequence:
MASKSQHNASKAKNHNVKAESQGQWGRAWEVDWFSLVSVIFLLLFAPFIVYYFIMACDQYSCSLTAPILDVATGRASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAGIVNKYEVNGLQAWLITHFLWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRTDGHCLIWGKKPKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF
  
Inhibitor
Name:
BDBM50406616
Synonyms:
CHEMBL268041
Type:
Small organic molecule
Emp. Form.:
C30H48N2O
Mol. Mass.:
452.7149
SMILES:
C[C@H](CCc1nccn1C)C1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)C1CC3 |c:16|
Structure:
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