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Target
Neuromedin-K receptor
Ligand
BDBM50406733
Substrate
n/a
Meas. Tech.
ChEMBL_141653 (CHEMBL857140)
Kd
7943.28±n/a nM
Citation
 Williams, BJ; Curtis, NR; McKnight, AT; Maguire, JJ; Young, SC; Veber, DF; Baker, R Cyclic peptides as selective tachykinin antagonists. J Med Chem 36:2-10 (1993) [PubMed]  Article 
Target
Name:
Neuromedin-K receptor
Synonyms:
NK3R_RAT | Neurokinin 3 receptor | Tac3r | Tacr3
Type:
n/a
Mol. Mass.:
51128.60
Organism:
Rattus norvegicus
Description:
ChEMBL_10983
Residue:
452
Sequence:
MASVPRGENWTDGTVEVGTHTGNLSSALGVTEWLALQAGNFSSALGLPATTQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLINFIYGLHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLFDPNDGDPTKSSRKKRAVPRDPSANGCSHRGSKSASTTSSFISSPYTSVDEYS
  
Inhibitor
Name:
BDBM50406733
Synonyms:
CHEMBL2370702
Type:
Small organic molecule
Emp. Form.:
C38H50N8O7S
Mol. Mass.:
762.918
SMILES:
CSCC[C@H]1NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(N)=O)NC1=O
Structure:
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