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Target
Protein Tat
Ligand
BDBM50407473
Substrate
n/a
Meas. Tech.
ChEMBL_199318 (CHEMBL805260)
IC50
2600±n/a nM
Citation
 Michne, WF; Schroeder, JD; Bailey, TR; Neumann, HC; Cooke, D; Young, DC; Hughes, JV; Kingsley, SD; Ryan, KA; Putz, HS Keto/enol epoxy steroids as HIV-1 Tat inhibitors: structure-activity relationships and pharmacophore localization. J Med Chem 38:3197-206 (1995) [PubMed]  Article 
Target
Name:
Protein Tat
Synonyms:
Human immunodeficiency virus type 1 Tat protein | Protein Tat | TAT_HV112 | Transactivating regulatory protein | tat
Type:
PROTEIN
Mol. Mass.:
9771.75
Organism:
Human immunodeficiency virus type 1 (isolate PCV12 group M subtype B)(HIV-1)
Description:
ChEMBL_199318
Residue:
86
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQGSQTHQVSLSKQPTSQSRGDPTGPKE
  
Inhibitor
Name:
BDBM50407473
Synonyms:
CHEMBL3137919
Type:
Small organic molecule
Emp. Form.:
C22H32O6S
Mol. Mass.:
424.551
SMILES:
[H][C@]12O[C@]11CC[C@@]3([H])[C@]4([H])CC[C@H](OC(C)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC(C2=O)S(C)(=O)=O
Structure:
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