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Target
Protein Tat
Ligand
BDBM50032828
Substrate
n/a
Meas. Tech.
ChEMBL_199318 (CHEMBL805260)
IC50
4000±n/a nM
Citation
 Michne, WF; Schroeder, JD; Bailey, TR; Neumann, HC; Cooke, D; Young, DC; Hughes, JV; Kingsley, SD; Ryan, KA; Putz, HS Keto/enol epoxy steroids as HIV-1 Tat inhibitors: structure-activity relationships and pharmacophore localization. J Med Chem 38:3197-206 (1995) [PubMed]  Article 
Target
Name:
Protein Tat
Synonyms:
Human immunodeficiency virus type 1 Tat protein | Protein Tat | TAT_HV112 | Transactivating regulatory protein | tat
Type:
PROTEIN
Mol. Mass.:
9771.75
Organism:
Human immunodeficiency virus type 1 (isolate PCV12 group M subtype B)(HIV-1)
Description:
ChEMBL_199318
Residue:
86
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQGSQTHQVSLSKQPTSQSRGDPTGPKE
  
Inhibitor
Name:
BDBM50032828
Synonyms:
7-Chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one | 7-chloro-5-(1H-pyrrol-2-yl)-1H-benzo[e][1,4]diazepin-2(3H)-one | CHEMBL91609 | Ro-5-3335
Type:
Small organic molecule
Emp. Form.:
C13H10ClN3O
Mol. Mass.:
259.691
SMILES:
Clc1ccc2NC(=O)CN=C(c3ccc[nH]3)c2c1 |t:9|
Structure:
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