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Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM82517
Substrate
n/a
Meas. Tech.
ChEMBL_1819 (CHEMBL616791)
Ki
1071.52±n/a nM
Citation
 Peglion, JL; Canton, H; Bervoets, K; Audinot, V; Brocco, M; Gobert, A; Le Marouille-Girardon, S; Millan, MJ Characterization of potent and selective antagonists at postsynaptic 5-HT1A receptors in a series of N4-substituted arylpiperazines. J Med Chem 38:4044-55 (1995) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rattus norvegicus (Rat)
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM82517
Synonyms:
2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione | CAS_107966 | CHEMBL126632 | CHEMBL8618 | NAN-190 | NSC_107966
Type:
Small organic molecule
Emp. Form.:
C23H27N3O3
Mol. Mass.:
393.4788
SMILES:
COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
Structure:
Search PDB for entries with ligand similarity: