Reaction Details Report a problem with these data
Target
Ribosyldihydronicotinamide dehydrogenase [quinone]
Ligand
BDBM50260401
Substrate
n/a
Meas. Tech.
ChEMBL_544427 (CHEMBL1016924)
IC50
67.61±n/a nM
Citation
 Du, H; Wang, J; Zhang, X; Hu, Z A novel quantitative structure-activity relationship method to predict the affinities of MT3 melatonin binding site. Eur J Med Chem 43:2861-9 (2008) [PubMed]  Article 
Target
Name:
Ribosyldihydronicotinamide dehydrogenase [quinone]
Synonyms:
Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone]
Type:
Protein
Mol. Mass.:
25917.25
Organism:
Homo sapiens (Human)
Description:
P16083
Residue:
231
Sequence:
MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
  
Inhibitor
Name:
BDBM50260401
Synonyms:
3-(2-(furan-2-carboxamido)ethyl)benzofuran-5-carboxamide | CHEMBL505118 | N-(2-(5-Methylcarbamoyl-benzo[b]furan-3-yl)ethyl)-furylcarboxamide
Type:
Small organic molecule
Emp. Form.:
C16H14N2O4
Mol. Mass.:
298.2934
SMILES:
NC(=O)c1ccc2occ(CCNC(=O)c3ccco3)c2c1
Structure:
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