Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50415224
Substrate
n/a
Meas. Tech.
ChEMBL_605172 (CHEMBL1067394)
Ki
19952.62±n/a nM
Citation
 Piergentili, A; Quaglia, W; Del Bello, F; Giannella, M; Pigini, M; Barocelli, E; Bertoni, S; Matucci, R; Nesi, M; Bruni, B; Di Vaira, M Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation. Bioorg Med Chem 17:8174-85 (2009) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1
Type:
Protein
Mol. Mass.:
51442.54
Organism:
Homo sapiens (Human)
Description:
P11229
Residue:
460
Sequence:
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50415224
Synonyms:
CHEMBL593685
Type:
Small organic molecule
Emp. Form.:
C11H24NO2
Mol. Mass.:
202.3132
SMILES:
C[C@H]1OC[C@@H](C[N+](C)(C)C)OC1(C)C |r|
Structure:
Search PDB for entries with ligand similarity: