Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50415319
Substrate
n/a
Meas. Tech.
ChEMBL_605640 (CHEMBL1070562)
EC50
>31622.78±n/a nM
Citation
 Gleave, RJ; Beswick, PJ; Brown, AJ; Giblin, GM; Goldsmith, P; Haslam, CP; Mitchell, WL; Nicholson, NH; Page, LW; Patel, S; Roomans, S; Slingsby, BP; Swarbrick, ME Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB(2) agonists for the treatment of inflammatory pain. Bioorg Med Chem Lett 20:465-8 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50415319
Synonyms:
CHEMBL595450
Type:
Small organic molecule
Emp. Form.:
C14H13Cl2N3O
Mol. Mass.:
310.179
SMILES:
Clc1ccc(c(Cl)c1)-c1ccc(nn1)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: