Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 6
Ligand
BDBM50420185
Substrate
n/a
Meas. Tech.
ChEMBL_836539 (CHEMBL2077176)
Ki
22700±n/a nM
Citation
 Enomoto, A; Takeda, M; Taki, K; Takayama, F; Noshiro, R; Niwa, T; Endou, H Interactions of human organic anion as well as cation transporters with indoxyl sulfate. Eur J Pharmacol 466:13-20 (2003) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
hPAHT | PAH transporter | Renal organic anion transporter 1 | hOAT1 | hROAT1 | Organic anion transporter 1 | S22A6_HUMAN | SLC22A6 | OAT1 | PAHT
Type:
PROTEIN
Mol. Mass.:
61831.78
Organism:
Human
Description:
ChEMBL_1487359
Residue:
563
Sequence:
MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQTRQQQEHQKYMVPLQASAQEKNGL
  
Inhibitor
Name:
BDBM50420185
Synonyms:
CHEMBL1233636
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: