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Target
Monocarboxylate transporter 10
Ligand
BDBM92690
Substrate
n/a
Meas. Tech.
ChEMBL_838252 (CHEMBL2076200)
Ki
3100000±n/a nM
Citation
 Kim, DK; Kanai, Y; Chairoungdua, A; Matsuo, H; Cha, SH; Endou, H Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem 276:17221-8 (2001) [PubMed]  Article 
Target
Name:
Monocarboxylate transporter 10
Synonyms:
Aromatic amino acid transporter 1 | MCT 10 | MOT10_RAT | Mct10 | Slc16a10 | Solute carrier family 16 member 10 | T-type amino acid transporter 1 | Tat1
Type:
PROTEIN
Mol. Mass.:
55663.29
Organism:
Rattus norvegicus
Description:
ChEMBL_838252
Residue:
514
Sequence:
MVPSLEEPAAAERETNEAQPPGPAPSDDAPLPVPGPSDVSDGSVEKVEVELTRSTGNQEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLFLAGFTYRPLVPSSKEKESEDSRSSFFSRRKLSPPKKIFNFALFKETAYAVWAAGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFMCIGVTSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLTSMMIPLCSVFGALIALCLIMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHSKKQREISKNTGGEKMEKMLANQSSLLSSSSGIFKKESDSII
  
Inhibitor
Name:
BDBM92690
Synonyms:
L-Abrine, 12
Type:
Small molecule
Emp. Form.:
C12H12N2O2
Mol. Mass.:
216.2359
SMILES:
[O-]C(=O)C(Cc1c[nH]c2ccccc12)[NH+]=C
Structure:
Search PDB for entries with ligand similarity: