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Target
P2Y purinoceptor 6
Ligand
BDBM50421165
Substrate
n/a
Meas. Tech.
ChEMBL_839562 (CHEMBL2090458)
EC50
60±n/a nM
Citation
 Ginsburg-Shmuel, T; Haas, M; Grbic, D; Arguin, G; Nadel, Y; Gendron, FP; Reiser, G; Fischer, B UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety. Bioorg Med Chem 20:5483-95 (2012) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50421165
Synonyms:
CHEMBL2086765
Type:
Small organic molecule
Emp. Form.:
C20H30BN4O21P3
Mol. Mass.:
766.199
SMILES:
B[P@@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(OC)c(=O)[nH]c1=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(OC)c(=O)[nH]c1=O |r|
Structure:
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