Reaction Details Report a problem with these data
Target
Fibroblast growth factor 1
Ligand
BDBM50421304
Substrate
n/a
Meas. Tech.
ChEMBL_840110 (CHEMBL2090813)
Kd
174000±n/a nM
Citation
 Liu, L; Li, C; Cochran, S; Feder, D; Guddat, LW; Ferro, V A focused sulfated glycoconjugate Ugi library for probing heparan sulfate-binding angiogenic growth factors. Bioorg Med Chem Lett 22:6190-4 (2012) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 1
Synonyms:
Acidic fibroblast growth factor | Beta-endothelial cell growth factor | ECGF-beta | FGF1 | FGF1_HUMAN | FGFA | Fibroblast growth factor 1 (FGF-1) | HBGF-1 | Heparin-binding growth factor 1 | aFGF
Type:
Protein
Mol. Mass.:
17461.01
Organism:
Homo sapiens (Human)
Description:
P05230
Residue:
155
Sequence:
MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
  
Inhibitor
Name:
BDBM50421304
Synonyms:
CHEMBL2087897
Type:
Small organic molecule
Emp. Form.:
C13H20N2O20S4
Mol. Mass.:
652.561
SMILES:
CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)COS([O-])(=O)=O |r|
Structure:
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