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Target
Motilin receptor
Ligand
BDBM50421353
Substrate
n/a
Meas. Tech.
ChEMBL_122667 (CHEMBL732797)
pH
2.5±n/a
Temperature
298.15±n/a K
IC50
71±n/a nM
Comments
extracted
Citation
 Koga, H; Sato, T; Tsuzuki, K; Onoda, H; Kuboniwa, H; Takanashi, H Potent, acid-stable and orally active macrolide-type motilin receptor agonists, GM-611 and the derivatives Bioorg Med Chem Lett 4:1347-1352 (1994)    Article 
Target
Name:
Motilin receptor
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
43771.25
Organism:
Oryctolagus cuniculus
Description:
n/a
Residue:
400
Sequence:
MGSPWNGSDGPEDAREPPWAALPPCDERRCSPFPLGTLVPVTAVCLGLFAVGVSGNVVTVLLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGQLLCRLSLYVGEGCTYASLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAALWAVALLSAGPFFFLVGVEQDPAVFAAPDRNGTVPLDPSSPAPASPPSGPGAEAAALFSRECRPSRAQLGLLRVMLWVTTAYFFLPFLCLSILYGLIARQLWRGRGPLRGPAATGRERGHRQTVRVLLVVVLAFIVCWLPFHVGRIIYINTQDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAARRLLRESRAGPSGVCGSRGPEQDVAGDTGGDTAGCTETSANTKTAA
  
Inhibitor
Name:
BDBM50421353
Synonyms:
CHEMBL406517
Type:
Small organic molecule
Emp. Form.:
C37H67NO13
Mol. Mass.:
733.9268
SMILES:
CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
Structure:
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