Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50424174
Substrate
n/a
Meas. Tech.
ChEMBL_933559 (CHEMBL2319721)
IC50
25±n/a nM
Citation
 Tamura, Y; Hayashi, K; Omori, N; Nishiura, Y; Watanabe, K; Tanaka, N; Fujioka, M; Kouyama, N; Yukimasa, A; Tanaka, Y; Chiba, T; Tanioka, H; Nambu, H; Yukioka, H; Sato, H; Okuno, T Identification of a novel benzimidazole derivative as a highly potent NPY Y5 receptor antagonist with an anti-obesity profile. Bioorg Med Chem Lett 23:90-5 (2012) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY5R_MOUSE | Neuropeptide Y receptor Y5 | Neuropeptide Y receptor type 5 (NPY Y5) | Npy5 | Npy5r
Type:
Enzyme
Mol. Mass.:
52807.91
Organism:
Mus musculus (Mouse)
Description:
O70342
Residue:
466
Sequence:
MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
  
Inhibitor
Name:
BDBM50424174
Synonyms:
CHEMBL2312065
Type:
Small organic molecule
Emp. Form.:
C17H18N2O3S
Mol. Mass.:
330.401
SMILES:
CCS(=O)(=O)c1ccc2nc(OCCc3ccccc3)[nH]c2c1
Structure:
Search PDB for entries with ligand similarity: