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Target
Carbonic anhydrase 5B, mitochondrial
Ligand
BDBM50426823
Substrate
n/a
Meas. Tech.
ChEMBL_942145 (CHEMBL2341301)
Ki
>100000±n/a nM
Citation
 Riafrecha, LE; Rodríguez, OM; Vullo, D; Supuran, CT; Colinas, PA Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases. Bioorg Med Chem 21:1489-94 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 5B, mitochondrial
Synonyms:
CA-VB | CA5B | CAH5B_HUMAN | Carbonate dehydratase VB | Carbonic Anhydrase VB | Carbonic anhydrase 5B (CA VB) | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase 5B, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VB (CA VB)
Type:
Enzyme
Mol. Mass.:
36440.83
Organism:
Homo sapiens (Human)
Description:
Human (cloned) isozyme
Residue:
317
Sequence:
MVVMNSLRVILQASPGKLLWRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVDLVPGGDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVIGVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDYVLNVQAKPKPATSQATP
  
Inhibitor
Name:
BDBM50426823
Synonyms:
CHEMBL2323140
Type:
Small organic molecule
Emp. Form.:
C16H20O7
Mol. Mass.:
324.3258
SMILES:
OC[C@H]1O[C@@H](CC(=O)C=Cc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@H]1O |r,w:8.7|
Structure:
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