Reaction Details Report a problem with these data
Target
Placenta growth factor
Ligand
BDBM50428819
Substrate
n/a
Meas. Tech.
ChEMBL_942634 (CHEMBL2339396)
Kd
23±n/a nM
Citation
 Pesca, MS; Dal Piaz, F; Sanogo, R; Vassallo, A; Bruzual de Abreu, M; Rapisarda, A; Germanò, MP; Certo, G; De Falco, S; De Tommasi, N; Braca, A Bioassay-guided isolation of proanthocyanidins with antiangiogenic activities. J Nat Prod 76:29-35 (2013) [PubMed]  Article 
Target
Name:
Placenta growth factor
Synonyms:
PGF | PGFL | PLGF | PLGF_HUMAN
Type:
PROTEIN
Mol. Mass.:
24794.98
Organism:
Homo sapiens (Human)
Description:
ChEMBL_942634
Residue:
221
Sequence:
MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVELTFSQHVRCECRHSPGRQSPDMPGDFRADAPSFLPPRRSLPMLFRMEWGCALTGSQSAVWPSSPVPEEIPRMHPGRNGKKQQRKPLREKMKPERCGDAVPRR
  
Inhibitor
Name:
BDBM50428819
Synonyms:
GERANIN B
Type:
Small organic molecule
Emp. Form.:
C30H24O11
Mol. Mass.:
560.505
SMILES:
O[C@H]1Cc2c(O)cc3O[C@@]4(Oc5cc(O)cc(O)c5[C@@H]([C@H]4O)c3c2O[C@@H]1c1ccc(O)cc1)c1ccc(O)c(O)c1 |r,TLB:16:18:20:8.7.22,12:11:20:8.7.22|
Structure:
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