Reaction Details Report a problem with these data
Target
Protein S100-B
Ligand
BDBM50429682
Substrate
n/a
Meas. Tech.
ChEMBL_947124 (CHEMBL2341094)
IC50
6800±n/a nM
Citation
 Yoshimura, C; Miyafusa, T; Tsumoto, K Identification of small-molecule inhibitors of the human S100B-p53 interaction and evaluation of their activity in human melanoma cells. Bioorg Med Chem 21:1109-15 (2013) [PubMed]  Article 
Target
Name:
Protein S100-B
Synonyms:
S-100 protein beta chain | S100B | S100B_HUMAN
Type:
PROTEIN
Mol. Mass.:
10701.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_947124
Residue:
92
Sequence:
MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE
  
Inhibitor
Name:
BDBM50429682
Synonyms:
CHEMBL2335383
Type:
Small organic molecule
Emp. Form.:
C10H13N3O2
Mol. Mass.:
207.2291
SMILES:
COc1cc2n(C)c(=O)n(C)c2cc1N
Structure:
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