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Target
Tyrosine-protein phosphatase non-receptor type 2
Ligand
BDBM50429857
Substrate
n/a
Meas. Tech.
ChEMBL_942407 (CHEMBL2344761)
IC50
45900±n/a nM
Citation
 Saifudin, A; Tanaka, K; Kadota, S; Tezuka, Y Sesquiterpenes from the rhizomes of Curcuma heyneana. J Nat Prod 76:223-9 (2013) [PubMed]  Article 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 2
Synonyms:
PTN2_HUMAN | PTPN2 | PTPT | T-cell protein tyrosine phosphatase (TCPTP) | T-cell protein-tyrosine phosphatase | TC-PTP | TCPTP | Tyrosine-protein phosphatase non-receptor type 2 | Tyrosine-protein phosphatase non-receptor type 2 (TC-PTP)
Type:
Protein
Mol. Mass.:
48481.80
Organism:
Homo sapiens (Human)
Description:
P17706
Residue:
415
Sequence:
MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKATTAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
  
Inhibitor
Name:
BDBM50429857
Synonyms:
Aerugidiol | CHEMBL2332431
Type:
Small organic molecule
Emp. Form.:
C15H22O3
Mol. Mass.:
250.3334
SMILES:
[#6]\[#6](-[#6])=[#6]-1/[#6]-[#6@@H]2[C@@]([#6])([#8])[#6]-[#6][C@]2([#8])[#6](-[#6])=[#6]-[#6]-1=O |r,c:15|
Structure:
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