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Target
P2X purinoceptor 1
Ligand
BDBM50433072
Substrate
n/a
Meas. Tech.
ChEMBL_955889 (CHEMBL2379815)
IC50
71±n/a nM
Citation
 Jung, KY; Cho, JH; Lee, JS; Kim, HJ; Kim, YC Synthesis and structure-activity relationships of carboxylic acid derivatives of pyridoxal as P2X receptor antagonists. Bioorg Med Chem 21:2643-50 (2013) [PubMed]  Article 
Target
Name:
P2X purinoceptor 1
Synonyms:
P2RX1_MOUSE | P2rx1
Type:
PROTEIN
Mol. Mass.:
44863.39
Organism:
Mus musculus
Description:
ChEMBL_1280016
Residue:
399
Sequence:
MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSGLISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIMTPQQAQGHCAENPEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLHEAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKILHPLCPVFSLGYVVRESGQDFRSLAEKGGVVGITIDWECDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQNGTNRRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGEGERDPAATSSTLGLQENMRTS
  
Inhibitor
Name:
BDBM50433072
Synonyms:
CHEMBL2376126
Type:
Small organic molecule
Emp. Form.:
C16H15N3O10S2
Mol. Mass.:
473.434
SMILES:
Cc1nc(N=Nc2cc(ccc2S(O)(=O)=O)S(O)(=O)=O)c(CCC(O)=O)c(C=O)c1O |w:4.3|
Structure:
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