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Target
Sialidase-1
Ligand
BDBM50331692
Substrate
n/a
Meas. Tech.
ChEMBL_960639 (CHEMBL2390092)
IC50
620000±n/a nM
Citation
 Albohy, A; Zhang, Y; Smutova, V; Pshezhetsky, AV; Cairo, CW Identification of Selective Nanomolar Inhibitors of the Human Neuraminidase, NEU4. ACS Med Chem Lett 4:532-7 (2013) [PubMed]  Article 
Target
Name:
Sialidase-1
Synonyms:
NANH | NEU1 | NEUR1_HUMAN | Sialidase 1
Type:
PROTEIN
Mol. Mass.:
45463.28
Organism:
Homo sapiens (Human)
Description:
ChEMBL_960639
Residue:
415
Sequence:
MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
  
Inhibitor
Name:
BDBM50331692
Synonyms:
(2R,3R,4S)-3-acetamido-2-((1R,2R)-3-azido-1,2-dihydroxypropyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylate | CHEMBL1289311
Type:
Small organic molecule
Emp. Form.:
C11H16N4O7
Mol. Mass.:
316.2673
SMILES:
CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CN=[N+]=[N-])C(O)=O |r,c:7|
Structure:
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