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Target
N-arachidonyl glycine receptor
Ligand
BDBM50072775
Substrate
n/a
Meas. Tech.
ChEMBL_963378 (CHEMBL2388875)
IC50
5990±n/a nM
Citation
 Rempel, V; Volz, N; Gläser, F; Nieger, M; Bräse, S; Müller, CE Antagonists for the orphan G-protein-coupled receptor GPR55 based on a coumarin scaffold. J Med Chem 56:4798-810 (2013) [PubMed]  Article 
Target
Name:
N-arachidonyl glycine receptor
Synonyms:
G-protein coupled receptor 18 | GPCRW | GPR18 | GPR18_HUMAN | NAGly receptor
Type:
PROTEIN
Mol. Mass.:
38150.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107601
Residue:
331
Sequence:
MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSNINSEML
  
Inhibitor
Name:
BDBM50072775
Synonyms:
2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxy-propyl)-cyclohexyl]-phenol | 5-(1,1-Dimethyl-heptyl)-2-[(4R,6R)-5-hydroxy-2-((R)-3-hydroxy-propyl)-cyclohexyl]-phenol | CHEMBL48552 | CP-55940 | CP-55940 [(-)-AC],XIV | CP55,940 | CP55940 | ChEMBL_75020
Type:
Small organic molecule
Emp. Form.:
C24H40O3
Mol. Mass.:
376.5726
SMILES:
CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1 |r|
Structure:
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