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Target
G protein-coupled receptor GPR35
Ligand
BDBM50436000
Substrate
n/a
Meas. Tech.
ChEMBL_964307 (CHEMBL2395569)
EC50
4170±n/a nM
Citation
 Funke, M; Thimm, D; Schiedel, AC; Müller, CE 8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35. J Med Chem 56:5182-97 (2013) [PubMed]  Article 
Target
Name:
G protein-coupled receptor GPR35
Synonyms:
GPR35
Type:
PROTEIN
Mol. Mass.:
34295.07
Organism:
Rattus norvegicus
Description:
ChEMBL_107605
Residue:
306
Sequence:
MNNTNCSILPWPAAVNHIFTIYLVLLLVLGLLLNGLALWVFCYRMHQWTETRVYMTNLAVADVCLLCSLPFVLYSLKYSTSDTPICQLSQGIYLVNRYMSISLVTAIAVDRYVAVRHPLRARELRSPRQAGAVCVALWVIVVTSLVLRWRLGIQEGGFCFSSQNRYNFSTTAFSLLGFYLPLAIVVFCSLQVVTALARRPATDVEQVEATQKATRMVWANLAVFIICFLPLHLILTVQVSLNLHTCAARNIFSRALTITAKLSDINCCLDAICYYYMAKEFQDASLRATASSTPHKSQDTQSLSLT
  
Inhibitor
Name:
BDBM50436000
Synonyms:
CHEMBL2392179
Type:
Small organic molecule
Emp. Form.:
C18H11BrClNO6
Mol. Mass.:
452.64
SMILES:
COc1ccc(C(=O)Nc2cc(Br)cc3c2oc(cc3=O)C(O)=O)c(Cl)c1
Structure:
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