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Target
Glycogen phosphorylase, liver form
Ligand
BDBM50211294
Substrate
n/a
Meas. Tech.
ChEMBL_972499 (CHEMBL2409981)
Ki
29800±n/a nM
Citation
 Bokor, E; Docsa, T; Gergely, P; Somsák, L C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase. ACS Med Chem Lett 4:612-5 (2013) [PubMed]  Article 
Target
Name:
Glycogen phosphorylase, liver form
Synonyms:
Glycogen phosphorylase, liver form | Lgp | Liver glycogen phosphorylase | PYGL_RAT | Pygl
Type:
PROTEIN
Mol. Mass.:
97489.46
Organism:
Rattus norvegicus
Description:
ChEMBL_1491377
Residue:
850
Sequence:
MAKPLTDQEKRRQISIRGIVGVENVAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQAGTKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEITKKTFAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFPKDIDRMRRMSLIEEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVGDDIFLREIAKVKQENKLKFSQFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPNQPDLFKDIINMLFYHDRFKVFADYEAYVKCQEKVSQLYMNQKAWNTMVLRNIAASGKFSSDRTIREYAKDIWNMEPSDLKISLSKESSNGVNANGK
  
Inhibitor
Name:
BDBM50211294
Synonyms:
(7R,8S,9S,10R)-8,9,10-trihydroxy-7-hydroxymethyl-2-thioxo-6-oxa-1,3-diaza-spiro[4.5]decan-4-one | CHEMBL232698
Type:
Small organic molecule
Emp. Form.:
C8H12N2O6S
Mol. Mass.:
264.256
SMILES:
OC[C@H]1OC2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O
Structure:
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