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Target
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Ligand
BDBM50437693
Substrate
n/a
Meas. Tech.
ChEMBL_974341 (CHEMBL2411920)
IC50
22300±n/a nM
Citation
 Okada, K; Ye, YQ; Taniguchi, K; Yoshida, A; Akiyama, T; Yoshioka, Y; Onose, J; Koshino, H; Takahashi, S; Yajima, A; Abe, N; Yajima, S Vialinin A is a ubiquitin-specific peptidase inhibitor. Bioorg Med Chem Lett 23:4328-31 (2013) [PubMed]  Article 
Target
Name:
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Synonyms:
Neuron cytoplasmic protein 9.5 | PGP 9.5 | PGP9.5 | UCH-L1 | UCHL1 | UCHL1_HUMAN | Ubiquitin thioesterase L1
Type:
PROTEIN
Mol. Mass.:
24819.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_974327
Residue:
223
Sequence:
MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA
  
Inhibitor
Name:
BDBM50437693
Synonyms:
VIALININ A
Type:
Small organic molecule
Emp. Form.:
C34H26O8
Mol. Mass.:
562.5654
SMILES:
Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1
Structure:
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