Reaction Details Report a problem with these data
Target
P2X purinoceptor 4
Ligand
BDBM50446060
Substrate
n/a
Meas. Tech.
ChEMBL_1283887 (CHEMBL3106338)
IC50
14900±n/a nM
Citation
 Tian, M; Abdelrahman, A; Weinhausen, S; Hinz, S; Weyer, S; Dosa, S; El-Tayeb, A; Müller, CE Carbamazepine derivatives with P2X4 receptor-blocking activity. Bioorg Med Chem 22:1077-88 (2014) [PubMed]  Article 
Target
Name:
P2X purinoceptor 4
Synonyms:
ATP receptor | P2RX4_MOUSE | P2rx4 | P2x4 | Purinergic receptor
Type:
PROTEIN
Mol. Mass.:
43443.55
Organism:
Mus musculus
Description:
ChEMBL_1283887
Residue:
388
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIPDKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAGHSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKRYYYRDKKYKYVEDYEQGLSGEMNQ
  
Inhibitor
Name:
BDBM50446060
Synonyms:
CHEMBL3103385
Type:
Small organic molecule
Emp. Form.:
C21H24N2O
Mol. Mass.:
320.4281
SMILES:
CC(C)N(C(C)C)C(=O)N1c2ccccc2C=Cc2ccccc12 |c:17|
Structure:
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