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Target
von Hippel-Lindau disease tumor suppressor
Ligand
BDBM50446135
Substrate
n/a
Meas. Tech.
ChEMBL_1288131 (CHEMBL3110591)
Kd
240000±n/a nM
Citation
 Dias, DM; Van Molle, I; Baud, MG; Galdeano, C; Geraldes, CF; Ciulli, A Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? ACS Med Chem Lett 5:23-28 (2014) [PubMed]  Article 
Target
Name:
von Hippel-Lindau disease tumor suppressor
Synonyms:
Protein G7 | VHL | VHL_HUMAN | Von Hippel-Lindau disease tumor suppressor | Von Hippel-Lindau disease tumor suppressor protein (VBC) | pVHL
Type:
Protein
Mol. Mass.:
24136.87
Organism:
Homo sapiens (Human)
Description:
P40337
Residue:
213
Sequence:
MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD
  
Inhibitor
Name:
BDBM50446135
Synonyms:
CHEMBL3108879
Type:
Small organic molecule
Emp. Form.:
C12H17N3O4
Mol. Mass.:
267.2811
SMILES:
CNC(=O)[C@@H]1C[C@@H](O)CN1C(=O)Cc1cc(C)no1 |r|
Structure:
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