Target
Arginase
Ligand
BDBM50349826
Substrate
n/a
Meas. Tech.
ChEMBL_1286565 (CHEMBL3110798)
IC50
13700±n/a nM
Citation
 de Sousa, LRRamalho, SDBurger, MCNebo, LFernandes, JBda Silva, MFIemma, MRCorrêa, CJde Souza, DHLima, MIVieira, PC Isolation of arginase inhibitors from the bioactivity-guided fractionation of Byrsonima coccolobifolia leaves and stems. J Nat Prod 77:392-6 (2014) [PubMed]  Article 
Target
Name:
Arginase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
36149.67
Organism:
Leishmania amazonensis
Description:
ChEMBL_107995
Residue:
329
Sequence:
MEHVQQYKFYKEKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKASDNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFSWVPQVLKPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISDGRAIARCMMGETLLYTPHTSSKL
  
Inhibitor
Name:
BDBM50349826
Synonyms:
SYRINGARESINOL
Type:
Small organic molecule
Emp. Form.:
C22H26O8
Mol. Mass.:
418.437
SMILES:
COc1cc(cc(OC)c1O)[C@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1cc(OC)c(O)c(OC)c1 |r|
Structure:
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