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Target
CD209 antigen
Ligand
BDBM50448402
Substrate
n/a
Meas. Tech.
ChEMBL_1292691 (CHEMBL3123558)
IC50
1020000±n/a nM
Citation
 Tomašic, T; Hajšek, D; Švajger, U; Luzar, J; Obermajer, N; Petit-Haertlein, I; Fieschi, F; Anderluh, M Monovalent mannose-based DC-SIGN antagonists: targeting the hydrophobic groove of the receptor. Eur J Med Chem 75:308-26 (2014) [PubMed]  Article 
Target
Name:
CD209 antigen
Synonyms:
C-type lectin domain family 4 member L | CD209 | CD209_HUMAN | CD_antigen=CD209 | CLEC4L | DC-SIGN | DC-SIGN1 | Dendritic cell-specific ICAM-3-grabbing non-integrin 1
Type:
PROTEIN
Mol. Mass.:
45768.84
Organism:
Homo sapiens (Human)
Description:
ChEMBL_104194
Residue:
404
Sequence:
MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA
  
Inhibitor
Name:
BDBM50448402
Synonyms:
CHEMBL3121699
Type:
Small organic molecule
Emp. Form.:
C18H29N3O11
Mol. Mass.:
463.4364
SMILES:
COC(=O)[C@H]1C[C@H](OCCN=[N+]=[N-])[C@H](C[C@@H]1C(=O)OC)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O |r|
Structure:
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