Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50005287
Substrate
n/a
Meas. Tech.
ChEMBL_1291359 (CHEMBL3117775)
EC50
490±n/a nM
Citation
 Nanda, KK; Henze, DA; Della Penna, K; Desai, R; Leitl, M; Lemaire, W; White, RB; Yeh, S; Brouillette, JN; Hartman, GD; Bilodeau, MT; Trotter, BW Benzimidazole CB2 agonists: design, synthesis and SAR. Bioorg Med Chem Lett 24:1218-21 (2014) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50005287
Synonyms:
CHEMBL3114530
Type:
Small organic molecule
Emp. Form.:
C21H25N3O
Mol. Mass.:
335.4427
SMILES:
CCn1c(nc2c(cccc12)-c1ccccc1)C(=O)NCC(C)(C)C
Structure:
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