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Target
Metallo-beta-lactamase L1 type 3
Ligand
BDBM50008093
Substrate
n/a
Meas. Tech.
ChEMBL_1337987 (CHEMBL3241394)
IC50
1000±n/a nM
Citation
 McGeary, RP; Schenk, G; Guddat, LW The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-ß-lactamases and arginases. Eur J Med Chem 76:132-44 (2014) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase L1 type 3
Synonyms:
BLA1_STEMA | Beta-lactamase L1
Type:
PROTEIN
Mol. Mass.:
30803.13
Organism:
Stenotrophomonas maltophilia
Description:
ChEMBL_1500319
Residue:
290
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
  
Inhibitor
Name:
BDBM50008093
Synonyms:
CHEMBL3234717
Type:
Small organic molecule
Emp. Form.:
C21H19N3O7S
Mol. Mass.:
457.456
SMILES:
COC(=O)C(CSc1cc(C(=O)OC)c2nc3cccc(C(O)=O)c3nc2c1)NC(C)=O
Structure:
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