Reaction Details Report a problem with these data
Target
Metallo-beta-lactamase type 2
Ligand
BDBM50008094
Substrate
n/a
Meas. Tech.
ChEMBL_1338365 (CHEMBL3240241)
Ki
23000000±n/a nM
Citation
 McGeary, RP; Schenk, G; Guddat, LW The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-ß-lactamases and arginases. Eur J Med Chem 76:132-44 (2014) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase type 2
Synonyms:
BLAB_BACFG | Beta-lactamase type II | ccrA | cfiA
Type:
PROTEIN
Mol. Mass.:
27252.87
Organism:
Bacteroides fragilis
Description:
ChEMBL_1502123
Residue:
249
Sequence:
MKTVFILISMLFPVAVMAQKSVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVNQYIESTSKP
  
Inhibitor
Name:
BDBM50008094
Synonyms:
CHEMBL3234724
Type:
Small organic molecule
Emp. Form.:
C6H15NO4S
Mol. Mass.:
197.253
SMILES:
OS(O)([O-])CC[NH+]1CCOCC1
Structure:
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