Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50238959
Substrate
n/a
Meas. Tech.
ChEMBL_1352085 (CHEMBL3267350)
Ki
476±n/a nM
Citation
 de Lera Ruiz, M; Lim, YH; Zheng, J Adenosine A2A receptor as a drug discovery target. J Med Chem 57:3623-50 (2014) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50238959
Synonyms:
2-isopropyl-4-(thiazol-2-yl)thieno[3,2-d]pyrimidine | CHEMBL407307
Type:
Small organic molecule
Emp. Form.:
C12H11N3S2
Mol. Mass.:
261.366
SMILES:
CC(C)c1nc(-c2nccs2)c2sccc2n1
Structure:
Search PDB for entries with ligand similarity: