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Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50014380
Substrate
n/a
Meas. Tech.
ChEMBL_1350718 (CHEMBL3266103)
EC50
544±n/a nM
Citation
 Ye, XY; Morales, CL; Wang, Y; Rossi, KA; Malmstrom, SE; Abousleiman, M; Sereda, L; Apedo, A; Robl, JA; Miller, KJ; Krupinski, J; Wacker, DA Synthesis and structure-activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists. Bioorg Med Chem Lett 24:2539-45 (2014) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50014380
Synonyms:
CHEMBL3261132
Type:
Small organic molecule
Emp. Form.:
C27H39N5O3S
Mol. Mass.:
513.695
SMILES:
CCCc1cnc(nc1)N1CCC(CC1)C1Cc2cc(ccc2O1)N1CCN(CC1)S(=O)(=O)CCC
Structure:
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