Reaction Details Report a problem with these data
Target
Delta-aminolevulinic acid dehydratase
Ligand
BDBM50017193
Substrate
n/a
Meas. Tech.
ChEMBL_1365593 (CHEMBL3297374)
IC50
500000±n/a nM
Citation
 Lentz, CS; Halls, VS; Hannam, JS; Strassel, S; Lawrence, SH; Jaffe, EK; Famulok, M; Hoerauf, A; Pfarr, KM wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs. J Med Chem 57:2498-510 (2014) [PubMed]  Article 
Target
Name:
Delta-aminolevulinic acid dehydratase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
36671.06
Organism:
Wolbachia sp. subsp. Brugia malayi (strain TRS)
Description:
ChEMBL_108383
Residue:
331
Sequence:
MMFNFPNTRLRRRRSSKWVRNLTSESALSVNDLIFPLFVHDREETTELVSSLPGMKCYSIDGLVSIAQEAEDLGINAVAIFPVVDSKLKSENAEEAYNSDNLICKAIRAIKLKVPGIGIIADVALDPYTTHGHDGILKSNQIDVENDKTVSILCKQALALAKAGCNIVASSDMMDGRVGRIRKVLDDNNLQDVSILSYAVKYCSSFYAPFRQIVGSCVSSNSIDKSGYQMDYRNAREAICEIEMDLNEGADFIMVKPGMPYLDIIKMASDEFNFPIFAYQVSGEYAMIKAATNNGWLDYDKVIYESLVGFKRAGASAIFTYAALDVAKNLR
  
Inhibitor
Name:
BDBM50017193
Synonyms:
CHEMBL3287369
Type:
Small organic molecule
Emp. Form.:
C9H8N2O2
Mol. Mass.:
176.172
SMILES:
Cn1cnc2cc(ccc12)C(O)=O
Structure:
Search PDB for entries with ligand similarity: